Tromix
Oral powder for use in veterinary medicine
Pharmacotherapeutic group: Systemic antimicrobial, antibacterial agent
Description: Homogeneous powder, color ranges from light yellowish to yellow.
Target species: Cattle, small ruminants, pigs, rabbits, poultry.
Composition:
1 g of powder contains:
Sulfadimidine sodium – 200 mg
Trimethoprim – 40 mg
Tetracycline hydrochloride – 110 mg
Excipients: Bromhexine hydrochloride, sodium cyclamate, sodium citrate, saccharin, colloidal anhydrous silica, sodium chloride, lactose, pecuaroma 1226-Z.
Pharmacological properties:
Tromix is a broad-spectrum, long-acting antibacterial agent. Its pharmacological effect is due to the antimicrobial activity of its active components. The combination of substances provides a pronounced synergistic effect and exhibits bacteriostatic activity against most Gram-positive and Gram-negative bacteria: Escherichia coli, Clostridium spp., Salmonella spp., Proteus mirabilis, Proteus spp., Pasteurella spp., Staphylococcus spp., Streptococcus spp., Enterococcus spp., Klebsiella spp., Bordetella spp., Neisseria spp.
The combination of antibiotics and sulfonamides is highly effective against pathogenic microorganisms by inhibiting tetrahydrofolic acid synthesis in bacterial cells. Tetracycline disrupts protein biosynthesis in harmful bacteria at the ribosomal level.
The product is well absorbed from the gastrointestinal tract, reaching the bloodstream within 1–2 hours, and remains effective for up to 12 hours. Maximum blood concentration is reached 8 hours after administration. Excreted mainly with urine and partly with feces.
According to its effect on the body, Tromix belongs to hazard class IV (low-risk substances).
Effective against infections caused by microorganisms sensitive to sulfadimidine, trimethoprim, and tetracycline hydrochloride, including infections of the respiratory tract, digestive tract, urogenital system, and secondary bacterial infections. Well tolerated by the target animals and poultry when used at the recommended doses.
Indications for use:
For treatment of bacterial infectious diseases in cattle, small ruminants, pigs, poultry, and rabbits.
Cattle: pasteurellosis, respiratory diseases (pneumonia, bronchitis), enteritis.
Small ruminants (sheep, goats): dysentery, pneumonia, necrotic pododermatitis.
Pigs: pneumonia, gastroenteritis, septicemia.
Poultry: enteritis (colibacillary enteritis), complicated chronic respiratory disease, rhinitis.
Rabbits: rhinitis, pasteurellosis, enteritis (colibacillary enteritis).
Administration and dosage:
Administered orally with water or feed for 3–4 days.
Cattle, small ruminants, pigs: First day – 3 g/30 kg b.w.; following days – 2 g/30 kg b.w.
(1 kg product diluted in 2000 L water or mixed with 1000 kg feed).
Poultry, rabbits: First day – 2 g/L water; 2nd–3rd days – 1 g/L water.
If symptoms persist, repeat the treatment course after 3–4 days.
For newborn animals, use half of the adult dose. In severe cases, the daily dose may be doubled for the first two days.
Contraindications:
Do not use in animals with hypersensitivity to any of the components.
Adverse reactions:
In animals with renal insufficiency, water retention and edema may occur.
Overdose:
Overdose may cause water retention in animals with renal insufficiency. Edema subsides after using anti-edema agents.
Withdrawal period:
Meat: poultry – 5 days; cattle, small ruminants, pigs, rabbits – 5 days.
Packaging: 50 g polyethylene bag.
Storage conditions: Store in a dry, light-protected place at +5 to +25 °C.
Shelf life: 3 years.
Manufacturer: LLC “Biotecsi”, Georgia
